Esat-6 as an Effective Mycobacterium Tuberculosis Subunit Vaccine
نویسندگان
چکیده
Tuberculosis is still one of the important infectious diseases and a major cause for public health problems, particularly in lowand middle-income countries. Prevention of this disease is a priority of WHO. Many antigens have been candidate for vaccination. Evaluating the safety and efficacy of these antigens is the concern of many researchers. This review is about ESAT-6 as an effective Mycobacterium tuberculosis Subunit vaccine.
منابع مشابه
Cloning and Expression of Mycobacterium Tuberculosis ESAT-6 in Prokaryotic System
The identification of a large number of antigens with potential for development of new tuberculosis vaccine has been accomplished in recent years. This study was designed for cloning and expression of ESAT-6 as a potent antigen of Mycobacterium tuberculosis. Selected gene (Rv3875) was amplified by PCR and product was ligated into expressing plasmid vector pQE30 and recombinant pQE30-ES plasmi...
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